I'm an associate professor at Toronto Metropolitan University (formerly Ryerson University) in the Department of Mathematics. My current focus is the systemic response of a host to cancer and its treatment. Specifically, I study cancer immunology, the dynamics of heterogeneous cell populations in cancer progression, the role of the tumour microenvironment in intercellular communication and tumour development, and cancer treatments through the lens of quantitative systems pharmacology. I use a systems approach that integrates experimental data with mathematical models to create predictive tools for hypothesis testing and exploration. You can check out my research here
My publications can be found on google scholar.
My History
My post-doctoral training was in an interdisciplinary cancer lab, the Center of Cancer Systems Biology, in Boston, MA. While there, I was also a Research Instructor at Tufts University School of Medicine. My research studied cancer-immune interactions leading to tumour dormancy, and cancer cachexia, the irreversible loss of muscle and adipose tissue due to cancer progression.
My Doctorate examined Cerebrospinal Fluid Pulsations and Aging Effects in Mathematical Models of Hydrocephalus in the Applied Mathematics department at the University of Waterloo (UW). Together with my collaborator (C. Drapaca) and my advisor (S. Sivaloganathan), we developed several mathematical models to investigate mechanical effects of CSF pulsations on the brain, as well as the effect of aging on brain tissue mechanical properties. We used these mathematical tools to test several medical hypotheses for the development of hydrocephalus.
My Masters work researched information theoretic methods to locally register regions of interest in images with specific applications to medical imaging. In the summer of 2002, I attended the Atlantic Association for Research in the Mathematical Sciences (AARMS) summer school, held at Memorial University in St. John's, Newfoundland.
Recent News
I am now co-chair of the Centre for Math Medicine at the Fields Institute.
I am the graduate program director for the math department at TMU. We have both MSc and PhD programs.
Lab Members
Current lab members can be found on our Biomath and Fluids website. All members are listed here.Current Openings
If you are interested in mathematical oncology research at TMU please contact me. I may have openings for undergraduate research assistants, MSc, PhD, and postdoctoral positions.